University of Chicago Research Specialist 2 in Chicago, Illinois
20123 Ob & Gynecology
About the Unit
The ovarian cancer research laboratory was established at the University of Chicago in 2004. Our main goals include: 1. Understand the early steps of ovarian cancer metastasis to the peritoneum and omentum 2.Characterize tumor – stroma interactions in ovarian cancer, including the communications between adipocytes, fibroblasts, mesothelial cells and cancer cells 3.Identify new treatment targets and evaluate the efficacy of these therapeutics in pre-clinical models to prepare for their translation into the clinic 4.Investigate the validity of agents that are effective treatments in other cancers to delay or inhibit the development of ovarian cancer 5.Utilize advanced proteomics analysis methods to gain further insights into ovarian cancer biology and develop tools for ovarian cancer detection and treatment.
The ovarian cancer research laboratory is looking for a Research Specialist 2 to join its ovarian cancer research team. Specifically, the Research Specialist 2 will be investigating the role of and therapeutic targets of the stroma during ovarian cancer disease progression, and will involve human tissue, in vivo mouse, three-dimensional organotypic, and primary cell models to perform translational research. The Research Specialist 2 will work collaboratively with the principal investigators, fellows, students and other research specialists. Under limited direction, the incumbent performs complex lab and/or research-related duties and tasks.
- Assists with planning, development and execution of research in the laboratory
- Assists in organizing and managing the laboratory
- Participates in writing reports and manuscripts
- Works collaboratively with the team and collaborators
- Assists in management of animal colony and animal experiments
- Conducts periodic training for current and new members of the laboratory
- Contributes to, and sometimes leads, the writing of academic papers, reports and final summaries
- Collects, records, and analyzes data
- Conducts literature reviews.
- Ensures compliance with institutional, state, and federal regulatory policies, procedures, directives, and mandates
- May serve as a lead research specialist
- Presenting research findings at staff meetings, seminars, and scientific conferences
- Collaboration and Independence
- Attention to detail
*Education, Experience and Certifications:*
- Bachelor's degree in field relevant to the research (e.g., biology, cell biology, cancer biology) required
- Advanced degree in field relevant to the research (e.g., biology, cell biology, cancer biology) strongly preferred
- At least two years of relevant research experience, including:
- Molecular Biology techniques (i.e. quantitative real-time PCR, RNA and DNA isolation, transfection, infection, transformation, cloning)
- Biochemical techniques (i.e. immunoblots, affinity chromatography)
- Tissue Culture techniques (i.e. ex vivo cultures, primary cell isolation, transfection, infection, co-culture, three-dimensional modeling)
- Cell assays (i.e. adhesion, migration, invasion, proliferation, apoptosis, cytotoxicity)
- Drug screening
- Microscopy (i.e. immunofluorescent analysis, wound healing assay, immunohistochemical analysis)
- Mouse in vivo models of cancer metastasis (i.e. intraperitoneal injections and dissections)
- Transgenic mouse models (i.e. breeding and genotyping)
*Technical Knowledge or Skills:*
- Knowledge in cancer biology and role of microenvironment during cancer progression
- Knowledge of research techniques or methods (cell biology, translation, transcription, primary cultures, microscopy, cell assays, biochemical assays, molecular biology assays)
- Knowledge of regulatory policies and procedures
- Strong interest in and commitment to research goals of laboratory
- Required a minimum of two year of experience in research.
- Comfort working with a team required
- Ability to be flexible in changing research focus required
- Experience contributing to research manuscripts, reports, or publications preferred
- Cover Letter
- Reference Contact Info
NOTE: When applying, all required documents MUST be uploaded under the Resume/CV section of the application
Depends on Qualifications
Scheduled Weekly Hours
Job is Exempt?
Drug Test Required?
Does this position require incumbent to operate a vehicle on the job?
Health Screen Required?
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- Posted 18 Days Ago
- Full time